Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Research groups

Hebe Chen

Postdoctoral Scientist

I began my research career as an undergraduate at the University of Reading, where I specialised
in Biomedical Sciences. I then further completed a Masters in Immunology at King’s College London
(KCL), and carried out my dissertation in breast cancer research, under the supervision of
Professor Joy Burchell at Guy’s Hospital. I received my PhD degree in Immunology (2016) from
KCL, where I investigated ‘the immuno-modulatory roles of vitamin D and alpha1-antitrypsin
in human lung diseases’ in Professor Catherine Hawrylowicz’s lab. I subsequently and briefly
worked as a research associate in the Hawrylowicz lab, before joining the University of Oxford
as a postdoctoral researcher. I work with Holm Uhlig and Arian Laurence on the following projects. 

Current projects:                          

-Investigating the role of transcription factor BACH2 in human T and B cells and its relationship
with colitis and common variable immune deficiency. This involves phenotypic characterisation
of new cohorts with heterozygous mutations of BACH2.
-Characterising different mutations in IL-6ST (encoding the human cytokine receptor subunit GP130)
and to investigate its impact on GP130 dependent cytokine signalling pathways including IL-6 and IL-11.