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Contact information


chantal.hargreaves@ndm.ox.ac.uk

Research groups

Chantal Hargreaves

Dr

Postdoctoral Scientist

I’m interested in how genetic variation impacts on the immune system in health and disease, and how using cutting-edge genomic technologies can advance our understanding of immunodeficiency, autoimmunity and cancer.

I became interested in immunology during my undergraduate degree in Medical Sciences at the University of Birmingham. I completed my PhD at King’s College London in 2012, investigating the role of somatic hypermutation in generating autoreactive antibodies in autoimmune thyroid disease. I moved to the University of Southampton for a postdoctoral position investigating whether genetic variation at the Fc gamma receptor locus influences the success of monoclonal antibody therapy in cancer.

In 2016 I joined the lab of Dr Smita Patel at the University of Oxford as a postdoctoral scientist. My current projects include investigating the genetic basis of Common Variable Immunodeficiency Disorder using high-throughput DNA sequencing and identifying novel disrupted pathways using RNA sequencing.

Research interests

Immunodeficiency, autoimmunity, blood cancer, antibodies, B cells, genomics

Recent publications

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