I am a DPhil student in Holm Uhlig's lab investigating anti-microbial pathways in inflammatory bowel disease (IBD). I studied Biochemistry and quickly became captivated by the field of immunology, leading me to pursue an MSc in Integrated Immunology. The complexity of IBD enthralled me and I therefore embarked upon my current DPhil project focused on a monogenic disorder that presents with IBD-like inflammation, namely Hermansky-Pudlak Syndrome (HPS). HPS patients have defects in the biogenesis of lysosome-related organelles, and we are trying to identify and characterize the pathways involved in order to elucidate the etiology of IBD in these patients.
Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ
Swan DJ. et al, (2019), Haematologica, 104, e483 - e486
Crohn's Disease in Niemann-Pick Disease Type C1: Caught in the Cross-Fire of Host-Microbial Interactions.
Cavounidis A. and Uhlig HH., (2018), Digestive diseases and sciences, 63, 811 - 813