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Pleurodesis is used to obliterate the pleural space and is an effective therapeutic option for patients with recurrent effusions or pneumothoraces. A variety of surgical methods and chemical pleurodesing agents exist with different efficacy and side effect profiles. Talc is the most common and most effective agent available for chemical pleurodesis. Pleurodesis remains an important treatment modality for management of malignant effusions even with the advent of indwelling pleural catheters. There is growing interest to predict markers of successful pleurodesis and its role in patient survival.

Original publication





Book title

Encyclopedia of Respiratory Medicine, Second Edition

Publication Date





590 - 606