Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The colonic faecal and mucosal associated bacterial populations of five patients with ulcerative colitis and four control patients were studied in detail to assess their ability to produce IgA1-proteases. A total of 330 bacterial strains were isolated from the patients with ulcerative colitis and IgA1-protease activity was unable to be reliably shown in any. It is therefore unlikely that such enzyme production by colonic bacteria plays a significant role in the pathogenesis of ulcerative colitis.

Type

Journal article

Journal

Gut

Publication Date

02/1987

Volume

28

Pages

186 - 189

Keywords

Bacteria, Colitis, Ulcerative, Colon, Feces, Female, Humans, Immunoglobulin A, Immunoglobulin A, Secretory, Intestinal Mucosa, Male, Peptide Hydrolases, Serine Endopeptidases