Tamsin Cargill
DPhil student
Brief biography:
I have been working with the Barnes group alongside my clinical training for several years. Much of my work has been focused on translational cellular immunology in immune mediated hepatobiliary disease. Recently I have been awarded a Welcome Trust Clinical Fellowship to undertake a PhD on HBV immunotherapy within the vaccine group.
Research Interests:
I am interested in harnessing cellular immunology to understand disease pathogenesis and develop novel treatment strategies for hepatobiliary conditions.
Current projects:
IgG4-Related Disease Study: Natural history and pathogenesis
Immunotherapy for chronic Hepatitis B infection
Recent publications
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HBV001: Phase I study evaluating the safety and immunogenicity of the therapeutic vaccine ChAdOx1-HBV.
Journal article
Cargill T. et al, (2023), JHEP reports : innovation in hepatology, 5
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NK cells limit therapeutic vaccine-induced CD8+T cell immunity in a PD-L1-dependent manner.
Journal article
Diniz MO. et al, (2022), Science translational medicine, 14
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Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study.
Journal article
Marjot T. et al, (2021), Journal of hepatology, 74, 567 - 577
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The Role of B Cells and B Cell Therapies in Immune-Mediated Liver Diseases.
Journal article
Cargill T. and Culver EL., (2021), Frontiers in immunology, 12
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What is the probability that this patient, who presents to a UK hospital, will be diagnosed with Covid-19? Prospective validation of the open-source CovidCalculatorUK resource
Preprint
Chapman G. et al, (2020)