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UNLABELLED: The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6 months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13). TRIAL REGISTRATION NUMBER: ISRCTN 34164388.

Original publication

DOI

10.1136/thoraxjnl-2014-205958

Type

Journal article

Journal

Thorax

Publication Date

02/2015

Volume

70

Pages

181 - 182

Keywords

Cytokine Biology, Sleep apnoea, Biomarkers, C-Reactive Protein, Continuous Positive Airway Pressure, Humans, Inflammation, Interleukin-10, Interleukin-6, Patient Compliance, Sleep Apnea, Obstructive, Tumor Necrosis Factor-alpha